The Lasso Lab works at the intersection of computational biology and virology. We apply computational approaches—including structural bioinformatics, network biology, and machine learning—to study sequence-to-structure-to-function relationships in viral and host proteins that drive infection by (re)emerging zoonotic viruses.
With globalization and climate change accelerating viral spillover and outbreak risks, our work aims to establish predictive and therapeutic strategies to mitigate future pandemics. Our research focuses on three key areas:
The Zoonotic and Pathogenic Potential of Emerging Viruses
Host Genetic Variation in Viral Infections
Molecular Interactions Underpinning Viral Infection Diseases
Our laboratory thrives on collaboration, working closely with both experimental and computational groups within the UK and globally to drive multidisciplinary discoveries. Importantly, we are committed to fostering an inclusive, supportive, and intellectually stimulating environment.